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Lyophilised powder: freeze at -20 C or below immediately on receipt - stable for years Reconstituted solution: refrigerate at 28 C , use within 30 days , never freeze (ice crystals damage the peptide) Topical serums / creams: cool, dark storage

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The ability to shuttle between the +1, +2, and +3 oxidation states is responsible for the versatile chemistry of vitamin B 12 , allowing it to serve as a donor of deoxyadenosyl radical (radical alkyl source) and as a methyl cation equivalent (electrophilic alkyl source)