eli lilly glp-1 receptor agonist medications to seek approval of new weight-loss drug this year As GLP-1 Use Expands, Long-Term

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P =0.18), GLP-1 RA were associated with a significant reduction in the incidence of MACE compared with placebo and pioglitazone, with a non-significant trend towards reduction in DPP-4 inhibitor-controlled studies [100]

NLRP3 inhibitor Oridonin can suppress the expression of IL-18 and IL-1, alleviate inflammation, preserve myocardial function and improve myocardial remodeling by reducing NLRP3 expression [89]