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PPAR- ligands, such as Wy-14,643, were reported to have an antifibrotic action in the rat thioacetamide (TAA) model of liver cirrhosis [14]

Xie, H., Tang, S

Nadauld LD, Garcia S, Natsoulis G, Bell JM, Miotke L, Hopmans ES, Xu H, Pai RK, Palm C, Regan JF, Chen H, Flaherty P, Ootani A, Zhang NR, Ford JM, Kuo CJ, Ji HP

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Target metabolites and their corresponding internal standards were analyzed by using Agilent 1290 UHPLC coupled with an Agilent 6460 triple quadrupole mass spectrometer (Agilent Technologies, Santa Clara, CA, USA)