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Consistent with prior sequential target trial emulation studies 17 , we sequentially emulated 135 target trials constructed every consecutive month between January 2013 and March 2024 (Extended Data Fig

After all, the drugs delivered something previous generations of medications largely could not: meaningful and sustained weight loss

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cardiovascular and fibrosis endpoint studies favour semaglutide

1st Optimal providers can only prescribe medications after establishing a proper doctor-patient relationship through formal consultation, medical history review, and appropriate laboratory testing