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It has been suggested that reactive oxygen species (ROS) play an important role in the pathogenesis of airway inflammatory diseases (26,27)

Clinical translation: Inconsistent drug delivery within RA's complex microenvironment, patient diversity, manufacturing scalability issues, and stability limitations hinder effective treatment

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Beyond pellagra-research models and strategies addressing the enduring clinical relevance of NAD deficiency in aging and disease

This discrepancy between controlled trials and real-world evidence highlights the complexities of translating trial findings to diverse patient populations