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When no stability data exists for a specific formulation, USP chapters 795 and 797 provide default BUD values

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Based on the response surface methodology-central composite design (RSM-CCD), an optimum formulation of SA-SMEDDS, consisting of ethyl oleate (oil, 12.30%), Cremophor-EL (surfactant, 66.25%), 1,2-propanediol (cosurfactant, 21.44%), and drug loading (50 mg/g), was obtained

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They are typically soft, movable, and painless, making them easy to overlook