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In addition, the nongenetic surface modification of MSCs with sialyl Lewis X carbohydrate using a polyacrylamide linker and biotin/streptavidin interaction showed robust rolling on the endothelium and homed inflamed tissues in vivo more efficiently than unlabeled MSCs 46

a c ) Representative images of TH immunofluorescence of the whole SNc/VTA brain region from Trkb Penk-WT control ( a ), Trkb Penk-KO mutant injected with Gsto2 -shRNA ( b ) or scrambled-shRNA ( c ) in the striatum at 3 M

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Astrocyte, a promising target for mood disorder interventions