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2021 Jul 10

showed that the melanocortin-derived tripeptide KPV produced significant anti-inflammatory effects in DSS colitis and CD45RBhi transfer colitis models two of the most commonly used and accepted IBD research paradigms.1 Critically, the anti-inflammatory effect persisted even in animals with a nonfunctional MC1R receptor, confirming that KPV's action does not depend on melanocortin signaling

To determine if aging altered susceptibility to APAP, we characterized the mortality in 5, 10, and 30-day old flies with and without APAP treatment

Modulation of inflammatory response arising from high-intensity intermittent and concurrent strength training in physically active males

Sections of citrate antigen retrieval were incubated overnight with anti-mouse FAP antibody (#ab218164, Abcam, Cambridge, UK)