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Marques C, Hadjab F, Porcello A, Loureno K, Scaletta C, Abdel-Sayed P, Hirt-Burri N, Applegate LA, Laurent A

could be detected corroborating the studies showing absence of GSH synthesis in lactococci but possessing the ability to import and regenerate reduced glutathione

De novo synthesis of serine from the glycolytic intermediate 3-phosphoglycerate (3-PG) occurs through a pathway consisting of three sequential steps: phosphoglycerate dehydrogenase (PHGDH) oxidizes 3-PG to 3-phosphohydroxypyruvate (pPYR) using an NAD + cofactor, phosphoserine aminotransferase (PSAT) transaminates pPYR to phosphoserine (pSER) using glutamate as the nitrogen donor, and finally phosphoserine phosphatase (PSPH) dephosphorylates pSER to produce serine [68]

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In these scenarios, variety can be a bit of a hindrance