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Semaglutide may be an option if you struggle with hunger, have difficulty keeping weight off, or havent achieved meaningful results with diet and exercise alone

It activates GLP-1 receptors located in the pancreas, brain, and digestive system

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By five years, BMI change relative to the natural BMI trajectory (ie, no treatment) was estimated to be 2.2% with lifestyle counselling, 7.4% with liraglutide, 9.5% with mid-dose phentermine and topiramate, 10.8% with top-dose phentermine and topiramate, and 18.5% with semaglutide