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Estrogens positive influence on synaptic plasticity and neurogenesis is, therefore, critical for preserving brain function during menopause and aging [63]

In early drug discovery, assessing beta-arrestin recruitment helps determine whether a GPCR ligand induces receptor desensitization, internalization, or non-canonical signaling

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Curr Biol CB 28(4):R170-R85 McMahon J, Huang X, Yang J et al (2012) Impaired autophagy in neurons after disinhibition of mammalian target of rapamycin and its contribution to epileptogenesis [J]

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