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The version of the TwoSampleMR package used in this study was 0.5.6, which is available at 2.5 Phenome-wide association study (PheWAS) A gene-level PheWAS was carried out using data from the AstraZeneca PheWAS portal 4 to examine whether druggable genes might impact other traits ( p 5 were excluded ( 2.8 Construction of the H 2 O 2 -induced oxidative stress model SRA01/04 lens epithelial cells were cultured in DMEM medium containing 10% fetal bovine serum (FBS) and 1% penicillin/streptomycin, in a 37 C, 5% CO 2 incubator

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The onset of PD is associated with severely decreased levels of reduced glutathione (GSH) in the substantia nigra