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, which included 229 participants (97 with MAFLD and 132 non-MAFLD controls), GGT was found to be an independent risk factor for MAFLD (OR: 1.055

Studies have shown that the gut microbiota can convert dietary polyphenols into low molecular weight bioactive metabolites, such as short-chain fatty acids (SCFAs) and phenolic acids, which may exert their antioxidant and anti-inflammatory effects through signaling pathways like Nrf2 and NF-B (Balkrishna et al., 2024)

This difference persisted after adjusting for confounding factors such as age, sex, and apolipoprotein (Apo) E 4 genotype [47, 48]

But it may also indicate liver or bile duct problems, according to Mayo Clinic

Metformin is a well-established and effective medication for insulin resistance in PCOS, and it does important work