The medication's mechanism of slowing gastric emptying makes dietary modifications particularly important for tolerability
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As we explained in the CY 2025 PFS final rule (89 FR 98237), this policy is intended to hold beneficiaries harmless in situations where the payment amount is calculated differently from the specified amount, and we believe this approach is consistent with the statutory language and appropriately reflects the differences in the statutory text of section 1847A(i)(5) of the Act, which sets forth the payment amount that is used to determine whether coinsurance should be adjusted, and section 1847A(i)(3)(A) of the Act, which sets forth the specified amount used to determine rebate amounts
First, the number of dimensions were reduced using time-structure independent component analysis (tICA) 63,64