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Although the GAA altered MET availability in the dams (Motta et al., 2025), supplementation of GAA to heifers 63 days before breeding until d 63 of gestation, did not alter the methyl supply in fetal liver (Crouse et al., 2023)

Spezzini J, Piragine E, Flori L, Calderone V, Martelli A

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Animal research used weight-based dosing roughly in the range of 10 mcg per kg, which for a 80 kg human would be approximately 800 mcg per day, though extrapolation from rodent to human dose is not straightforward and this is not a clinical recommendation

doi: 10.1016/j.indcrop.2020.112463 133 TaoKGuoLHuXFitzgeraldCRouzardKHealyJet al