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In the MPTP mouse model, NRF2 activation has been associated with a reduction in oxidative stress (Williamson et al., 2012), induction of antioxidant enzymes (Townsend and Johnson, 2016) and astrocytic, and microglial activation were found to be significantly lower ( drosophila restored mitochondrial function, elevated mitophagy rates and suppressed oxidative stress ( NRF2 in Multiple Sclerosis MS is a chronic neurodegenerative and autoimmune disease that affects 2.8 million people worldwide and remains one of the most common causes of neurological disability in the young adult population (Ramanathan et al., 2001)

P Shivkar RR, Gawade GC, Padwal MK, Diwan AG, Mahajan SA, Kadam CY

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Microbiota metabolites modulate the T helper 17 to regulatory T cell (Th17/Treg) imbalance promoting resilience to stress-induced anxiety- and depressive-like behaviors

Suppressing pain blocks symptoms temporarily