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Of these 50 semaglutide-treated patients that developed anti-semaglutide antibodies, 28 patients (1.6% of the overall population) developed antibodies cross-reacting with native GLP-1.The in vitro neutralizing activity of the antibodies is uncertain at this time

If patients experience concerning or persistent injection site reactions, they should discuss these with their healthcare provider rather than assuming such reactions are too minor to report

Smith I, Ivkovic M, Plotkin M et al

Prioritize Sleep We know this is easier said than done, but try to get a good night's sleep each night

Patients with cirrhosis require ongoing surveillance for hepatocellular carcinoma with ultrasound (with or without alpha-fetoprotein) every six months, regardless of weight loss treatment