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However, for some Asians, Ashkenazi Jews and others whose gene pool contains a mutant or altered form of the ALDH2 gene, the toxic acetaldehyde isnt broken down as quickly, so it hangs around and accumulates in the liver and body resulting in what is known as the Asian glow

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They are contraindicated for individuals with medullary thyroid carcinoma or Multiple Endocrine Neoplasia type 2