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Endothelial dysfunction is characterized by suppressed production and utilization of nitric oxide associated with proinflammatory and prothrombotic properties

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Current NICE guidance (NG49) emphasises lifestyle modification as the primary treatment for NAFLD, including weight loss, dietary changes, and increased physical activity

assessed bioavailability of apigenin and its O-glycosides in healthy male adults, administered as an apigenin capsule, parsley, as a drink or dried with yogurt, or chamomile tea (191, 188, 14.5 mol, respectively) which demonstrated poor absorption of apigenin and intra- and inter- individual variations on level of its metabolite secretions [151]

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