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If the efficacy readouts from SURMOUNT-1 are reproducible, Lilly almost certainly has a best-in-class medication this may be plainly reflected in the SURMOUNT-5 Phase 3b trial readout (1H 2025)

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Passed: Validates the formulations acid/base balance to support comfortable administration

Consistency can be improved with physician supervision and proper instruction on nasal inhalation techniques

Much of semaglutide-associated nausea stems from delayed gastric emptying, food sitting in the stomach longer than normal, leading to a sensation of fullness and queasiness