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It is also evident that many of the antioxidant enzymes are induced by GSH depletion at the transcriptional level which involves the binding of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) transcription factor to the antioxidant response element (ARE) in the promoter region of the genes encoding GCL and glutathione S -transferases [16]

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If you're unfamiliar with how GHRPs differ from GHRH peptides and oral secretagogues, read our full breakdown: GHRH vs GHRP vs Secretagogues: The Mechanistic Difference

10.3390/ijms20010231 [DOI] [PMC free article] [PubMed] [Google Scholar] 162.Higashi Y, Aratake T, Shimizu T, Shimizu S, Saito M

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