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This ubiquitous protease is expressed in several tissues, including pancreatic -cells, and cleaves the amino-terminal dipeptide at the penultimate position with either L-proline or L-alanine (GLP-1), limiting the clinical utility of GLP-1 in T2DM patients, particularly its insulinotropic actions (Meier et al., 2006

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Pero, es cierto que tomar L-carnitina en ayunas potencia sus efectos

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The safety of taking goldenseal for longer periods is uncertain