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This association indicates that abnormalities in collagen and other connective tissue components may play a role in the diseases pathogenesis

Complete dosage chart for the 20mg/mL concentration: Notice the half-unit markings at 2.5mg (12.5 units) and 7.5mg (37.5 units)

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The human epitopes were derived from tissue antigens that are implicated in 10 ADs: rheumatoid arthritis (RA), ankylosing spondylitis (AS), autoimmune atherosclerosis (AIAS), psoriatic arthritis (PA), autoimmune thyroiditis (AIT), Sjogren's syndrome (SS), primary biliary cholangitis (PBC), type 1 diabetes mellitus (T1DM), multiple sclerosis (MS), and autoimmune uveitis (AU)