Archives of Internal Medicine
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These outcomes included magnitude of hemoglobin A 1c reduction, achievement of guideline-recommended HbA 1c targets, and weight loss, Dr
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The two dominant conjugation chemistries are: cysteine-based conjugation (reducing interchain disulfide bonds to generate free thiols, then reacting with maleimide-bearing linkers), which produces a heterogeneous mixture of DAR 0, 2, 4, 6, and 8 species
