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Lillys orfoglipron, a once-daily pill in the GLP-1 class, is another likely frontrunner, with promising results in mid-stage trials

FIGURE 1 ASD results from a complex interplay between genetic and environmental factors

Consider bigger lifestyle changes : GLP-1s work best when paired with a healthy diet (which helps you lose the weight) and regular exercise (to keep the weight off)

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Data show means and SD of estimated glomerular filtration rate (eGFR), alanine aminotransferase (ALAT), aspartate aminotransferase (ASAT), alkaline phosphatase (ALP), bilirubin and NAFLD liver fat score in response to each study drug in SIDD and SIRD participants, respectively, obtained at baseline (0) and after 6 months of treatment (eGFR was also measured at 3 months)