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And remember what I said about diet

The localized heat generated by RF can also temporarily increase lipid fluidity in the stratum corneum, promoting fusion of liposomal bilayers with disrupted skin lipids and enhancing the release of encapsulated drugs [261]

This review synthesizes evidence that probiotics mitigate UC through multiple synergistic mechanisms: competitive exclusion to rebalance the microbiota, upregulation of tight junction proteins to restore the intestinal barrier, and bidirectional immunomodulation to restrain excessive inflammation

B., Francesconi, M., Mittermayer, F., Schaller, G., Gouya, G., Wolzt, M., and Pleiner, J