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As more water is removed, stools become firmer, drier, and more difficult to pass

Kidney Int 59:230237

72 Although based primarily on anecdotal and case reports, concerns regarding risk of regurgitation and pulmonary aspiration due to delayed gastric emptying have resulted in guidance from the American Society of Anesthesiologists (ASA) Task Force on Preoperative Fasting for use of these medications prior to non-urgent or emergent procedures requiring general anesthesia

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Reduced expression of the androgen receptor by third generation of antisense shows antitumor activity in models of prostate cancer