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Methylation of arginine residues of histone and non-histone proteins are also thought to be an important regulator of cellular functions, in particular, the structure and function of DNA, so it may also contribute to epigenetic modifications [30] (Figure 2)

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Major histocompatibility complex susceptibility genes, including HLA-DR3, HLA-DR4, HLA-DQ2, and HLA-DQ8, are shared by both diseases

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