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The molecule retains only the 176191 C-terminal fragment of hGH, which carries the lipolytic signal but lacks the sequence regions responsible for IGF-1 elevation and growth-promoting activity

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Phase 3: mid titration (weeks 9 through 12) Semaglutide dose: 1.0 mg per week This dose represents a significant efficacy threshold

Some preliminary research also suggests potential benefits for cartilage and joint health, though this application requires further clinical investigation

These effects can be troublesome and may require dose adjustments or treatment discontinuation