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Today, endovenous thermal ablation techniques (laser and radiofrequency ablation) are considered the gold standard because they are highly effective and have short recovery times

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TGF- is a critical mediator in regulating tubular cell death and renal fibrosis under diabetic conditions

All molecules from the FDA approved drugs DrugBank subset and known inhibitors were subjected to the Openeye Blockbuster filter (part of the OMEGA suite version 4.1.2.0) to remove non-druglike compounds and limit the production of spurious hits [29]