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When researchers study how this enzyme behaves, they can observe how cellular energy pathways respond

Furthermore, the overexpression of -syn disrupts the interaction between mitochondria and the endoplasmic reticulum, interfering with Ca 2+ homeostasis and further inducing defects in mitochondrial fission (Tassone et al., 2023)

Since DDX3X does not appear to be required to infect cells 25 , the presence of DDX3X in mature virions is thus a remnant of its role during that step of the viral life cycle