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When freeze-drying is performed without a protective matrix (such as sucrose or mannitol), residual bound water may cause collapse during the final drying stage
In the current study, metformin was dissolved in saline for direct infusion into the small intestine, from where it would be rapidly absorbed
Supports gut lining integrity
Also, some PBMs now publish their PA forms online (e.g
requires careful consideration) Severe gastrointestinal disease (e.g., gastroparesis) Each patient is assessed individually to determine safety and appropriateness 6
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