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You can no longer be certain that the effects (or lack thereof) are due to the peptide itself

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In particular, histone deacetylases (HDAC) are potential therapeutic targets in different neurological conditions (Grff and Tsai, Another mechanism of epigenetic regulation is mediated by microRNAs, which cause the degradation of genes involved in the development and progression of BBB dysfunction (Figure 2) (Ma et al., Figure 2)

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