There is a growing body of evidence that NAD+ precursors can have anti-inflammatory effects
Interestingly, no difference in food intake was observed between wild-type mice treated with the dual incretin GLP-1/GIP coagonist and those treated with the tri-agonist despite the difference in weight loss, and this was found to be due to significantly higher ATP expenditure in tri-agonist-treated diet-induced obese mice
Cuturic, M., Abramson, R
Eur Heart J 27(18):21452146 Lee DS, Evans JC, Robins SJ, Wilson PW, Albano I, Fox CS, Wang TJ, Benjamin EJ, DAgostino RB, Vasan RS (2007) Gamma glutamyl transferase and metabolic syndrome, cardiovascular disease, and mortality risk: the Framingham heart study
Spread fluid intake evenly throughout the day rather than drinking large amounts at once, which can contribute to nausea or stomach discomfort