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Description

Approval status: Gonadorelin was FDA-approved historically as Factrel for diagnostic testing of pituitary gonadotropic function, and as Lutrepulse/Lutrelef delivered by pulsatile pump for hypothalamic amenorrhea

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Some researchers might prefer it if they hypothesize that rapid peak concentration is beneficial

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The mechanism may involve modulation of somatostatin (GH inhibitory hormone) release from the hypothalamus, or interaction with GHRH neurons

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[PMC free article: PMC389061] [PubMed: 5279528] 274

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This is expected, not failure

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