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However, caution is advised, as both may affect the digestive system and increase the likelihood of gastrointestinal side effects

Glucose-stimulated insulin secretion Mice were euthanized by cervical dislocation, followed immediately by clamping of the bile duct and perfusion with collagenase P (11249002001, Roche Diagnostics)

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It is also worth noting that these effects of liraglutide in OVX animals occurred relatively quickly, with positive outcomes observed after just four weeks of treatment, consistent with in vitro data [57]

The magnitude of between-group differences corresponded to large effect sizes at both 3 and 6 months (d = 1.08 and d = 1.31, respectively), indicating a clinically meaningful advantage for semaglutide