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However, 2D cultures oversimplify the cellular architecture and fail to capture the complex brain microenvironment ( in vitro models (Zivko et al., 2024)

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The glutathione detox pathway is not just about oestrogen

They concluded that melatonin and vitamin C treatment protected against citalopram-induced testicular injury by modulating nitrooxidative stress and apoptosis (Figure 1)