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It functions as a cofactor for lysyl oxidase (the enzyme responsible for collagen cross-linking and stabilization), ceruloplasmin (a copper transport protein with antioxidant activity), and superoxide dismutase (SOD, a primary antioxidant defense enzyme)
This compound represents a significant advancement in neuropharmacology as it was specifically engineered to overcome the limitations of its parent moleculeprimarily poor blood-brain barrier penetration and rapid metabolic degradation
PMID: 26552939 [6] Moore EM, Ames D, Mander AG, Carne RP, Brodaty H, Woodward MC, Boundy K, Ellis KA, Bush AI, Faux NG, Martins RN, Masters CL, Rowe CC, Szoeke C, Watters DA
From our previous study by cDNA microarray, the expression of growth hormone receptor gene was one of the most up-regulated in tendon fibroblasts treated with BPC 157
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