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Drinks high in sugar may also make blood sugar swings, cravings, or next-day fatigue worse for some people

Gallbladder disease, including cholelithiasis and cholecystitis, also occurs at higher rates in rapid weight-loss contexts

According to FDA prescribing information, gastrointestinal side effects vary by dose and indication, with nausea occurring in up to approximately 33% of patients taking Zepbound (with somewhat lower rates for Mounjaro)

(There are now pill forms of weight-loss drugs, but the injectable forms have been more popular because patients lose more weight with the injectable versions of the medications.) Can retatrutide reduce knee pain

Doctors play a key role in getting the best results