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Inspection of the trajectory of weight changes with time revealed that weight loss continued to progress in the CagriSema group up to the end of treatment at 32 weeks, whereas in the semaglutide and cagrinlitide groups, weight reduction seemed to approach a plateau [10]

However, theyre not a standalone weight loss solution

A randomised trial of GHRH analogues in older adults showed significant lean mass gains versus placebo over 26 weeks, alongside reductions in truncal fat.4 2

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Both support natural growth hormone production, but they work in slightly different ways