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New compounds emerge, and with them, a flurry of questions from the scientific community

Accessed January 15, 2026 New England Journal of Medicine

Exercise plus GLP-1 medication produces approximately 40% more weight loss, twice the body fat reduction, and improvements in fitness, blood sugar, insulin sensitivity, and bone health that medication alone cannot achieve

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Unlike synthetic GH injections, peptide therapy works gradually and naturally, encouraging the body to self-regulate hormone production for long-term benefits