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Why did the FDA restrict peptides in the first place

IGF Binding Proteins and Bioavailability The mechanism underlying this enhanced potency relates to IGF-1's complex regulatory system involving IGF binding proteins (IGFBPs), a family of six high-affinity binding proteins (IGFBP-1 through IGFBP-6) that normally sequester the vast majority of circulating IGF-1 and regulate its bioavailability, half-life, and access to cell surface IGF-1 receptors

In continuation selenium compounds in 2004 Back and co-workers reported for the first time that spirodioxyselenurane and its tellurium analogue exhibit very good antioxidant activity by mimicking the glutathione peroxidase (GPx) enzyme which protects the organism from oxidative damage by catalyzing the reduction of peroxides using thiol as the cofactor [47, 56]

But the drugs come with a multitude of side effects, too

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