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Also, in the same study, CAT enzyme activity before and after surgery was not found to be significant compared to the healthy control group 48

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While a significantly greater percentage of patients on semaglutide achieved MASH resolution with no worsening of fibrosis compared with placebo, there was no difference in improvement of fibrosis stage between treatment and placebo groups

Retatrutide is still unavailable outside of clinical trials, but that has not stopped a surge in illegal activity around the drug, with people claiming to buy and sell it on social media

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