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To account for the deal, Merck will take a $112 million pre-tax charge in its fourth quarter results
This, in turn, has been demonstrated to result in the up-regulation of PD-L1 expression, the reduction of CD4 and CD8 T-cell activation and tumor infiltration, and the promotion of the growth of pancreatic ductal adenocarcinoma (PDAC) cells [112]
Ricci, V., Giannouli, M., Romano, M
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165 Blocking TGF signaling can effectively mitigate the effects of aging transmission, providing a new direction for the treatment of aging-related diseases
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