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Lancet Neurol (2007) 6:3738 10.1016/S1474-4422(07)70077-7 [DOI] [PubMed] [Google Scholar] 66.Ohrui T, Tomita N, Sato-Nakagawa T, Matsui T, Maruyama M, Niwa K, et al

A well-designed trial, even with only a few dozen participants, can reveal important clues

UPC Label 1 / UPC Label 2 / UPC These statements have not been evaluated by the Food and Drug Administration

Obesitys reclassification as a chronic disease has been pivotal

Examples Repaglinide (Prandin) Dosage Initial: 0.52 mg before each meal, up to four times daily Maximum: 16 mg daily, 4 mg per dose Nateglinide (Starlix) Dosage Initial: 60120 mg before meals, up to three times daily Maximum: 360 mg daily, 120 mg per dose Possible side effects include: Hypoglycemia (lower risk than sulfonylureas) Weight gain Bile acid sequestrants Primary mechanism(s) of action Bile acid sequestrants were originally developed and approved to lower LDL-cholesterol