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While there has been no clear association with certain psychiatric side effects, such as depression or suicidal ideation in research-based 31 or real-world 32 samples, the potential modulation of reward pathways by these drugs necessitates vigilant monitoring in patients with psychiatric histories, particularly in the setting of treatment with a medication that can substantially modulate the response of appetitive neurocircuitry to natural rewards such as food and water

Gomez-Navarro, N

Angiotensin II Receptor Blockers (ARBs) Mechanism: Block Angiotensin II receptors vasodilation, aldosterone Examples: Losartan, Valsartan, Olmesartan Key Points: Alternative for patients who cannot tolerate ACE inhibitors (e.g., cough) 6

Vitamin B5 is a critical cofactor in metabolizing fats, proteins, and carbohydrates

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