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If elevated ROS and/or lower antioxidant activities are responsible for the damage done to gametes and embryos incubated in PF and FF of endometriosis patients, then the addition of antioxidants to PF and FF incubation medium should decrease rates of gamete and embryo damage

Data availability All data generated or analyzed during this study are included in this published article

Working this out was a major challenge because, as Lefkovits highlights, 'the spleen cell suspension contains millions of cells and from bulk cultures where all the cells are present it is simply impossible to deduce which contain the cell committed to antibody formation' (Lefkovits 2025)

Here's the key nuance: these side effects can occur even on a small dose