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In the published Phase I dose-escalation study in healthy adults, CJC-1295 with DAC showed good tolerability, with injection-site reactions reported as the most common adverse effect

By stimulating the GLP-1 and GIP pathways, as well as glucagon receptors, Retatrutide enables the study of integrated metabolic responses rather than isolated receptor activities

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GLP-1 medications are intended to be a long-term treatment to help manage obesity, in combination with a low-calorie diet and regular physical activity