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The BIs included neutral protamine Hagedorn insulin, insulin detemir, insulin glargine 300 U/ml (Gla-300), and insulin glargine 100 U/ml (Gla-100) or degludec (U-100 and U-200)

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(2012) performed a meta-analysis including 779 patients from three studies, which, however, the authors saw as seriously compromised by details of trial designs 19