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Studies show it significantly lowers HbA1c levels, a key measure of long-term blood sugar control

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It activates the GLP-1 receptor, which signals the pancreas to release insulin, slows gastric emptying, and reduces appetite.nnThree engineered changes to the native GLP-1 backbone (an Aib substitution at position 8, a Lys-to-Arg substitution at position 34, and a C18 fatty diacid attached at lysine 26) give semaglutide its long plasma half-life and once-weekly dosing profile

Brazils approval of EMSs Ozivy gives the country an early role in post-patent semaglutide competition, opening a synthetic follow-on route that could reshape pricing, access and Novo Nordisks dominance

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